Closebax® – Targeted Relief for Seborrhoeic Dermatitis and Dandruff

A targeted, clinically proven treatment system for seborrhoeic dermatitis and related scalp and facial irritation.

Seborrhoeic dermatitis is a chronic inflammatory condition linked to M alassezia yeast overgrowth, altered sebum composition, and barrier disruption. It can cause redness, scaling, itching, and discomfort on the scalp, face, beard line, and upper chest.

Closebax® is a dermocosmetic system designed to act on all four underlying causes — microbial imbalance, inflammation, excess sebum, and impaired barrier function — providing visible relief and long-term control.

The Closebax® System

A complete three-part regimen to normalise, soothe, and restore seborrhoeic skin.

Closebax® SD Shampoo

For: Greasy or dry dandruff, seborrhoeic dermatitis of the scalp

• Gently cleanses while regulating sebum and reducing microbial proliferation.
• Soothes irritation and restores scalp barrier integrity.
• Strengthens and brightens the hair.

Key actives:

• Piroctone Olamine – Antifungal and antibacterial, controls Malassezia and Staphylococcus species.
• MSM (Methylsulfonylmethane) – Reduces histamine, inflammation, and itching.
• Triethyl Citrate – Normalises sebum production, reduces inflammatory fatty acids.
• Vitamin PP (Niacinamide) – Rebalances sebum and supports the lipid barrier.
• Xylitol – Hydrates and restores keratin and ceramide synthesis.
Use:
• Intensive phase: Apply daily to wet hair, leave for 30–60 seconds, rinse.
• Maintenance: Use 2–3 times per week to prevent relapse.

Closebax® SD Lotion

For: Seborrhoeic dermatitis on scalp edges, beard line, or other hairy areas

• Hydroalcoholic leave-on lotion that enhances the action of Closebax® SD Shampoo.
• Quickly absorbed without greasiness.
• Reinforces anti-inflammatory and antimicrobial action.

Key actives:

• MSM – Boosts anti-inflammatory activity and reduces itching and redness.
• Hexamidine Diisethionate – Broad-spectrum antibacterial and antifungal action.
• Triethyl Citrate – Sebum regulation.
• Xylitol – Barrier support and hydration.

Use:

• Intensive phase: Apply daily in the evening, allowing it to act overnight.
• Maintenance: 2–3 times per week or as directed by your SkinMed clinician.

Closebax® Cream

For: Facial and body seborrhoeic dermatitis lesions

• Moisturising, soothing, and sebum-normalising cream.
• Reduces erythema, scaling, and discomfort.
• Helps re-establish a healthy microbiota and barrier.

Key actives:

• MSM – Anti-inflammatory and anti-itch effect.
• Triethyl Citrate – Protects sebaceous triglycerides and limits inflammatory lipid release.
• Ethy Linoleate – Restores essential fatty acids to repair barrier function.
• Vitamin PP – Strengthens skin defence and normalises oil balance.

Use:

• Daily: Apply morning and evening to affected areas after cleansing.
• Combine with clinic-led SkinMed protocols for accelerated results.

The Science Behind Closebax®

Seborrhoeic dermatitis arises from a cycle of yeast proliferation, sebum imbalance, oxidative stress, and inflammation.

Closebax® interrupts this cycle through four targeted actions:

1. Rebalances microbiota – controls Malassezia and Staphylococcus species.
2. Reduces inflammation – inhibits cytokines (IL-1α, IL-6, TNF-α) and histamine.
3. Normalises sebum composition – lowers pro-inflammatory lipid metabolites.
4. Restores barrier integrity – replenishes linoleic acid and ceramides.
Clinical studies show a 90–100% reduction in dandruff and irritation within 28 days, with high tolerance and satisfaction among all subjects tested.

Results You Can See

• 90% of users report reduced redness and flaking after 14 days
• 70% report less itching after 2 weeks, rising to 90% at 4 weeks
• 100% describe hair as stronger and brighter
• 100% of participants would repurchase Closebax®

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